Malaysian Health Minister Chua Soi Lek announced Wednesday his resignation after admitting being filmed in a sex video, BBC reported.
The widely circulated DVD recording showed the married father of three having sex with a female friend in a hotel room.
The DVDs are believed to be CCTV recordings made in an unknown hotel suite.
Mr Chua admitted Tueasday he was the person featured in the videos, shocking the whole nation.
"I would like to emphasise I did not make the tape myself," he explained.
"My family, wife and children have accepted my apology, " Mr Chua added.
As health minister, he has advocated giving out free condoms to reduce the spread of HIV, in the face of religious opposition.