The virus currently causing bird flu in humans appears to be developing resistance to the only drug that can so far combat the infection, BBC reports.

Oxford University researchers report two cases of patients in Vietnam who died after failing to respond to treatment with the drug Tamiflu.

The H5N1 variant of the bird flu virus has so far killed over 70 people in south east Asia.

Most of the victims were in close contact with infected birds, and at present the virus is not believed to pose a significant threat to the wider population. Experts fear the virus will mutate and gain the ability to pass easily from human to human.

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