At least 22 people were killed and another 21 injured in a twin shooting in a dorm and classroom at Virginia Tech on Monday, CNN reported.
A gunman opened fire, taking many casualtties before he was killed, police said.
On the Web site, Tech reported the shootings at opposite sides of the 2,600-acre campus at West Ambler Johnston, a co-ed residence hall that houses 895 people, and said there were "multiple victims" at Norris Hall, an engineering building.
All entrances to the campus were closed and classes cancelled through Tuesday. The students were asked to stay indoors, to lock the doors and stay away from windows.
Amie Steele, editor-in-chief of the campus newspaper, said one of her reporters at the dormitory reported "mass chaos."
The reporter said there were "lots of students running around, going crazy, and the police officers were trying to settle everyone down and keep everything under control," according to Steele.