US researchers have made a vaccine preventing weight gain in rats, opening way to further application in human treatments.

The vaccine prompts the body to produce antibodies against ghrelin, a hormone that stimulates hunger and weight gain.

Vaccinated rats put on less weight, while eating the same amount as those, which did not have the jab.

A UK obesity expert as quoted by the BBC said the Proceedings of the National Academy of Sciences study was interesting, but it might not be safe for people.

The researchers said the results demonstrated that active immunisation against ghrelin could be used to control weight gain and accumulation of fat tissue in mammals.

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